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119 > Image 119 of Minutes of the University of Kentucky Board of Trustees, 2010-03-09

Part of Minutes of the University of Kentucky Board of Trustees

6. U.S. Patent Application Serial Number: (t0 be assigned) Filed: November 19, 2009 Title: "Diacylglycerol Acetyltransferase Sequences and Related Methods Inventors: Drs. David Hildebrand (Plant and Soil Sciences), Runzhi Li (Biochemistry) and Tomoko Hatanaka (outside inventor) Technical Description: This invention relates to diacylglycerol acetyltransferase (DGAT) sequences and methods of using them. In particular, the invention relates to novel nucleic acid and amino acid sequences for DGAT and methods of using those sequences to increase production of epoxy fatty acids. Su1nmary: Plant seed oils may one day replace petroleum as the source of many industrial compounds. One interesting class of plant seed oils is the epoxy fatty acids, which are useful in the production of dyes, paints, adhesives, and plastics. Unfortunately, plant species which are amenable to agriculture do not contain high concentrations of epoxy fatty acids in their seeds. The inventors have discovered the genetic sequence of DGAT, which is responsible for the production of epoxy fatty acids in seeds. This enables DGAT genetic material to be introduced into agricultural crops, increasing the concentration of epoxy fatty acids in their seeds. 7. U.S. Patent Application Serial Number: (to be assigned) Filed: November 19, 2009 Title: "Compounds and Methods for Reducing the Occurrence of Post-Surgical Adhesions Inventors: Drs. Thomas D Dziubla, Eugene Kaplan and John Mark Medley (Chemical and Materials Engineering) Teclmical Description: This invention relates to compounds and methods for reducing the occurrence of post-surgical adhesions. In particular, this invention relates to reducing adhesions using polymeric compounds comprised of acrylic acid groups and ethylene glycol. Su1nmary: Post-surgical adhesions occur when surgically damaged human tissue becomes attached to adjacent tissue. These adhesions frequently cause new problems, leading to more than $1 billion spent each year for corrective surgery. The inventors have developed a class of compounds which, when applied to surgically injured tissue, reduce the forrnation of post-surgical adhesions. 8. U.S. Patent Application Serial Number: (to be assigned) Filed: December 3, 2009 Title: "Method for Supplementing the Diet and Ameliorating Oxidative Stress Inventor: Dr. Boyd E. Haley (Chemistry) Teclmical Description: This invention relates to the field of dietary supplements for mammals and, more particularly, to methods reducing oxidative stress through dietary supplementation. Su1nmary: Oxidation is a naturally occurring chemical reaction that has the capacity to injure or kill the cells of living tissues. Exposure to heavy metals such as mercury and lead can drastically increase the amount of harrnful oxidation in the tissues of animals. The inventor has developed a class of compounds which,