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9 > Image 9 of Kentucky Alumnus, 1988, no. 4

Part of Kentucky alumnus

l { rt . i liz |IIIIIIIIIOIIIIIIIIIIIIIIIIIIIIIIIIllIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIII r V , si ls ` ~ P E _ E l __ i i .. s { g : l>r.bys lungs, lacking this "oiling" , ssssr @ . substance, are stiff and difficult to open r . i P s l- l . and force air into. The infants have the _;L , ,,____ ,_- -`s.. . ~ __ _ i A additional biomechanical liability of _ , ~~r_, T jj , than muscles and a limited energy / T . _;.q;~ t , s l =- ` 3 _3 ' ** i` J g . . . ._,, s<;g ~.; ~ 1 *T * Q, E supply. Hence, the infants need help in _ L \ _ .. E ,. _ jg 5 _- HI l i breathing to survive. W _ _ " - _ r , . < _- l ` l 's*;~ . . . , $-,;:--2 ~ M , l x. _ f' , "7 >__g 1 ' _ The full-term babies in NICU, like sr _ W _ , ,___,__ g y _ all i l , mlmy premature ones, can be born _ . bw " " l J _1 _ - ll 5* with or quickly develop a respiratory , Q `- a.:.:il _ _ __ _ .2 Y ; disease such as pneumonia. The result *` _,__ _ _ ... r rj fl; as M ' . " ' ~ {"* ; is that the infants must be helped with ~ _ l - if / e * . l D jir _ oxygen and a ventilator which blows \ . _ g _, g -. , V ,| V, tiiey puffs of air into their lungs. A \ t _ t ' ` major problem with infant ventilators is t* of * Eli tli it while the baby must have the air l ` ; Rl , . . l forced into its lungs, that pressure often __ , F .~s:;` / c . causes tissue damage. Like an ii li eff`; l i 3 l or erextended balloon, the 9~lVOl1 may Thgmgg Pqoly gs studying r\l|QU irifbms grid the use of high frequency let ventilclors, o mochinc tho? J nipturc and allow air to escapc into the forces nar imo the lungs of bobles who otherwise eoulsluw brenlhe. gl g _ Q cl est cavity or cause a lung to collapse. pr w i I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I il ,_,.- i dt veloped in the late 1960s and E {V dtsigmdtOacCOmmOdatc6_81b A MORE DELICATE TOUCH NEEDED g E V lrlalllso l`lOWeVer> the eXPeelallOrlS rer The dramatic decline in the weight of no match up with how the ventilator i [ V. s . . . . . P j rl~ Survlval Or a Premature baby have babies who are now surviving has made mechanics are set with regard to the 1 ` l lllereaseel elramauealllb lll the lale_ the 1960s ventilator equipment obsolete actual lung mechanics." g Y 19605, Premature bables who Surlflverl for saving these tiny infants. The Beginning their work in 1978, `Q lllilglleel at lcast 3`rl lbS ln the mld*0 amount of pressure needed to expand a Cunningham and Desai spent four - late 1970s, success in saying a 2-3 lb- 5 1b_ infsmys lungs is considerably years building their own pulmonary Q 3 bi`bY Waslusl Sllerr of a mll;aele Tdv greater than what is needed for a ll/2 lb. function testing device with the help of : ;l ' ( . . . . . . C l1sham SaYS rrlllere S a 90 infant. As Dr. Cunningham explains, pulmonary specialist Deborah i , ll reem Chance Or sllrvlvel rer a 2 lb- "The tolerances and capacity of the Mynheir, computer programmer Diane g ~ lbiebb We even exbeel a ralr ebabee Or lungs of these infants vary greatly." Gagel, and a consultant, Peter i . , . ' 3 . . . . . v Slllvlval lbr a l /4 lb baby and We expect Cunningham and Desai are Burbank, from the UK bioengineering A 2 . I . . . . . . I lb save el rew Or the l and a l /2 lb- developing methods of application for and medical instrumentation r ' V > . . . . _, lllarltS ventilators sensitive enough for use on department. The researchers also `ll _ . . . . . . . . . . . . . . . . . . . . . . 1-1l/2 lb. and larger infants and are employed techniques used by the UK ` g _ establishing a data base so that College of Pharmacy faculty in ' if _ physicians can more accurately pulmonary function testing of small , . r determine the correct setting for the animals. T; . \_ ventilator. Presently, physicians set the "I knew nothing about computers or X H _ in T , , , , i.___ ventilatorchoosing pressure, amount electronics and my colleagues knew ale l`` ` li T `Z, K and rate at which the respiratory gases nothing about neorlatology, but Q_ _ .` ,_ t.4 ~ .,_ { are administeredbased on indirect together we were able to Successfully 1 ;_ V s t~` mcthgds Of lung ag5sment_ As assemble {l1 p21I`(S pUI`Cl'l2iSCl from as _ _, .., l Cunningham says, "The state of the various companies to reach the l _ art right now is to rely on xray pictures minaturization and sensitivity required I l if of the lungs, blood samples fOI` C&I`bOH to study Our tiny paticntsfr says l as = ___.l dioxide and oxygen levels, and an Cunningham, ` lil . ei examination by stethoscope. There is In 1981, the researchers used the . 7 ul<