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Image 9 of Kentucky Alumnus, 1988, no. 4

Part of Kentucky alumnus

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l { rt . i liz |IIIIIIIIIOIIIIIIIIIIIIIIIIIIIIIIIIllIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIII r· V , si ls ` ~ P E _ E l __ i i .. s { g : l>r.by’s lungs, lacking this "oiling" ‘ , ssssr @ . substance, are stiff and difficult to open r . i P · ····s l- · ‘l . and force air into. The infants have the »_;L , ,,____ ,_- ·-·——`s.. . ~ __ _ i A additional biomechanical liability of _ , ~~r_, T — jj ,» than muscles and a limited energy / T . _;.q;·~¥ t , s l ··=-· ` 3 _3 ' *°* · i` J g . . . — ._,, s»<;g’·’ ~.; · ~ 1 • ·— *T · · * Q, E supply. Hence, the infants need help in _ L ·\ _ —..» E ,. _ jg 5 _- HI l i breathing to survive. W ’” _ _ " - _ »r , . < _·- l·· · ·° `··‘ l '¢‘s¢·*;~ . . . , $-,;:--2 ~ M ·· , l ·x. _ f' , »···"7‘ >__g 1 ' _ The full-term babies in NICU, like sr _ W _§ , ,___,·__ g y _ · all i l , mlmy premature ones, can be born _ . bw ° "’ ‘ " l J · ’ _1 _ - ll 5* with or quickly develop a respiratory , Q `- · ·¤‘a·.·:.:il ‘_ _ __ ·_ .2 Y ; » disease such as pneumonia. The result ‘*”` _,__ _ _ ... r rj fl; as M ' . — ‘ " ‘ ' ~ {"* ; is that the infants must be helped with ~ _ l ‘ - if / e · · * —».‘ ” l D jir _» oxygen and a ventilator which blows \ . _ g _, g -. , V ,| V, tiiey puffs of air into their lungs. A \ ·t _ t '» ` major problem with infant ventilators is t* ” of * Eli tli it while the baby must have the air l `· ; Rl , é . . l forced into its lungs, that pressure often » __ , F .~s»:;` · /’ ° c . causes tissue damage. Like an · ii li eff`; — l i 3 l · or erextended balloon, the 9~lV€Ol1 may Thgmgg Pqoly gs studying r\l|QU irifbms grid the use of high frequency let ventilclors, o mochinc tho? J nipturc and allow air to escapc into the forces nar imo the lungs of bobles who otherwise eoulsluw brenlhe. gl g _ Q cl est cavity or cause a lung to collapse. pr w i I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I il ,_,.- i dt veloped in the late 1960s and E {V dtsigmdtOacCOmmOdatc6_81b· A MORE DELICATE TOUCH NEEDED g E V lrlalllso l`lOWeVer> the eXPeelallOrlS rer The dramatic decline in the weight of no match up with how the ventilator i [ V. s · . . . . . • P j rl‘~ Survlval Or a Premature baby have babies who are now surviving has made mechanics are set with regard to the 1 ` l lllereaseel elramauealllb lll the lale_ the 1960s ventilator equipment obsolete actual lung mechanics." g Y 19605, Premature bables who Surlflverl for saving these tiny infants. The Beginning their work in 1978, `Q ‘ lllilglleel at lcast 3`rl lbS· ln the mld‘*0 amount of pressure needed to expand a Cunningham and Desai spent four - late 1970s, success in saying a 2-3 lb- 5 1b_ infsmys lungs is considerably years building their own pulmonary Q 3 bi`bY Waslusl Sllerr of a mll;aele· T¤d¤v greater than what is needed for a ll/2 lb. function testing device with the help of : ;l · ' ‘ ( . . . . . · · . C l¤¤1¤sham SaYS· rrlllere S a 90 infant. As Dr. Cunningham explains, pulmonary specialist Deborah i ‘, ll‘ reem Chance Or sllrvlvel rer a 2 lb- "The tolerances and capacity of the Mynheir, computer programmer Diane g ~ lbiebb We even exbeel a ralr ebabee Or lungs of these infants vary greatly." Gagel, and a consultant, Peter i . , . ' 3 . . . . . v ‘ Slllvlval lbr a l /4 lb· baby and We expect Cunningham and Desai are Burbank, from the UK bioengineering A 2 . I . . . . . . ¤ I lb save el rew Or the l and a l /2 lb- developing methods of application for and medical instrumentation r ' V ’ > . . . . _, lll‘arltS· ventilators sensitive enough for use on department. The researchers also `ll ·_ · » . . . . . . . . . . . . . . . . . . . . . . 1-1l/2 lb. and larger infants and are employed techniques used by the UK ` g _ establishing a data base so that College of Pharmacy faculty in ' if ° _ physicians can more accurately pulmonary function testing of small , . r determine the correct setting for the animals. T; . \_ ventilator. Presently, physicians set the "I knew nothing about computers or X H —_ in T ‘ , , , , i’.__’_ ventilator——choosing pressure, amount electronics and my colleagues knew ale · l`` ` li ‘ · T `Z, K and rate at which the respiratory gases nothing about neorlatology, but Q_ _ .`— ,_ t.—4 ~ .»,_ { are administered—based on indirect together we were able to Successfully 1 ·;_ V s ’t‘~` mcthgds Of lung ag5€sment_ As assemble {l’1€ p21I`(S pUI`Cl'l2iS€Cl from as _‘ _, · ..,· l Cunningham says, "The state of the various companies to reach the l _ art right now is to rely on x—ray pictures minaturization and sensitivity required ° I l if of the lungs, blood samples fOI` C&I`bOH to study Our tiny paticntsfr says l as = ___.l dioxide and oxygen levels, and an Cunningham, ` lil ‘¤.· ei examination by stethoscope. There is In 1981, the researchers used the ‘ . 7 ul<