service providers that assist in analysis of microarray data, each providing unique
       services. Using multiple unrelated service providers requires that data from the
       experiment must be in a different format for each service provider. Ms. Gao and
       Dr. Hayes have invented a computer interface that allows the user to access
       multiple service providers using one data format.

3.     U.S. Patent Application Serial Number: (to be assigned)
       Filed: December 8, 2004
       Title: "Methods and Devices for Cryopreservation of Biological Cells and
       Tissues"
       Inventors: Dr. Dayong Gao, Dr. Gary Van Zant, and Dr. Xiang Dong Cui.
       Technical Description: The present invention provides novel methods and
       devices for achieving optimal cooling of cells during cryopreservation. In one
       aspect, the method comprises gradually cooling the cell to a predetermined
       temperature, followed by rapidly cooling the cell to a second predetermined
       temperature. In another aspect, a device is described for achieving a desired
       cooling rate for a cell, comprising a first container for holding a cell, and a second
       container for holding the first container whereby an insulating space is preserved
       between the first and second container. The method of the invention comprises
       placing cells into the first container, placing the first container in the second
       container, and sealing the second container. The first container, second container,
       and insulating space are dimensioned and fabricated of materials selected
       whereby an optimal cooling rate in accordance with a predetermined optimal
       cooling rate for the cell is achieved by simply placing the second container
       holding the first container and cells into a suitable cooling device.
       Summary: Drs. Gao, Van Zant, and Cui have invented methods and devices for
       optimal cryopreservation (preservation by freezing) of biological cells and tissues,
       and to cryoprotectant compositions. The invention also allows controlled cooling
       of various cell types during cryopreservation and maintaining optimal cooling
       rates according to the particular needs of specific cell types.

4.     U.S. Patent Application Serial Number: (to be assigned)
       Filed: December 21, 2004
       Title: "Vectors and Methods for Enhanced Cell Longevity and Protein
       Expression"
       Inventors: Dr. Bruce A. Webb and Mr. Jeremy Kroemer.
       Technical Description: The present invention provides methods and
       compositions relating to the expression of vankyrin proteins in cell lines to
       increase their viability, longevity, and capacity for protein production. The
       inventors have discovered that the expression of P-ank- 1 and 12-ank-3 proteins in
       cell culture has increased the cells' longevity and capacity for endogenous and/or
       heterologous target protein production. Specifically, the present invention relates
       to the enhanced expression of endogenous and/or heterologous target
       proteins/polypeptides in recombinant cells that are also expressing P-ank- 1 and/or
       I2-ank-3 protein compared to expression host cells that are not expressing P-ank-I
       and/or 12-ank-3 protein.