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I _    'A>' I I "THE COMMON THREAD BINDING THESE I
  ‘   V.   E SCIENTISTS TOGETHER IS THE FOCUS OF I
I -   I `II A THEIR RESEARCH ON BIOMEDICAL ISSUES  
I A W  4v_. HI ‘*"°AWAA1 I ~      AFFECTING HUMANS. WHILE THEY ARE
  A ` tj V A   ABSORBED IN THE WORK ON THEIR LAB
    BENCHES — OBSERVING CELLS, MOLECULAR
_ ·   _  I INTERACTIONS AND CHEMICAL PROCESSES —
I \     ,3 I" THEY ULTIMATELY SEEK TO UNDERSTAND  
I \
  5    Vix; WHAT HAPPENS WHEN THE HUMAN BODY IS I
I {  A   INJURED, ILL OR ADDICTED. THEIR I
I   LABORATORY DISCOVERIES ARE THE
I Q \ I‘   ’     I BUILDING BLOCKS UPON WHICH FUTURE I
, I— _A `7 7%.%. I MEDICAL TREATMENTS WILL BE FOUNDED. I
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I I,. ‘· I IT is POSSIBLE THAT A “EUREKA MOMENT”
‘  ·_ I         IN THE BBSRB wiLL LEAD TO AN I
·  ‘   II  I ADVANCED TREATMENT FOR SPINAL I
j 4 INJURIES, A BETTER UNDERSTANDING OF
I = E A R THE AGING PROCESS, OR A REVOLUTION IN `
I s · HOW DOCTORS TREAT ADDICTlON.” ‘
I     — WWW.UKY.EDU/RESEARCH
1 I     II         TTT’I {I  I  / /    ET    »TA "   A’“"‘““g IY all °II‘i1EI‘“§,‘§3I§§§§ ISI? IIIIIIIIIIIF II Ill WIII
. I   ‘ 1=_· I s t    I    _. I;      see tounng t roug e I . I u , irs e me e you
I I .;§ I ar  M · · / .»· J aa  ./.   I about this baby.The Biomedical Biological Sciences Research
I ‘ I ’   F Building will be a year old in April and it’s already making a dif-
I ,   .` _   ~   ference. lt houses some of the University of Kentucky’s leading
I I I I   A; BBSRB FACT SHEET   I II researchers — around 400 faculty, staff and students — whose I
I I   L • COST: $744 MILLION     work brings millions of dollars in federal funding to UK.
I' I ·$¤ZE¤ ISEOOOSQUAREFEET fi Y°“£i€1“i“£”$.2*%.52;*2‘*i.2;§.$.?;‘§;Z".;i’I‘1E§;?;i?.S$? I
I • Aacuiracr; VENTURA Scorr   ,9 ESSIIYC O exp O C P - q - · ‘ I
I I I >   solutions. That takes special spaces and special equipment. After I
I I I BROWN AND ASSOCIATES. INC-   all, if something goes wrong with your car, you`ve got to know `
I. • STEEL FRAME STRUCTURE ,  I H how it’s supposed to work before you can fix it, and you have to
I . I • FOUR FLQQRS QF "OI¤I{I\I-   have special gadgets and a place to park it while you work on it.
I I { , . . -
" IS         »# It S the SEIITIC Wlth blOITl€CllCHl I`€S€ElI`Ch.
I   In the lab of William Balke UK senior associate dean for clini-
I WITH CONFERENCE ROOM " . . . ’ .
’ , cal research, medicine and director of the Institute for Molecular
COMPUTER I-ABS I   Biology, the focus is on cardiovascular disease, the third leading
I _ • SPECIALIZED ROOMS FOR r cause of death in Kentucky, and a leading cause of death in the
»· SAMPLE STORAGE, LOW- United States. When Balke came to Kentucky he brought his en-
TEMPERATURE EXPERIIVIENTSI   tire lab with him from the University of Maryland to the BBSRB
PRO-IEIN ANALYSIS CELL   as including about 20 faculty, postdoctoral students and staff as well
’ as six research projects. His team first discovered ion “channels"
  CULTURE WORK AND EQUIP- set up by certain cell proteins and calcium that seem to move
  IVIENT- through the heart in a way to trigger a steady beat. lf the theory I
__I • BASEMENT ANIMAL D|AGNOS· holds up what tests show to date, then it is possible that a drug- I
I   TIC FACILITY VI/ITI-I AUTOIVIATIC based alternative treatment could be developed to treat deadly, ir-
I   WAS]-EDELIVERY SYSTEM regLIlarly beatigg he1aLt;i1$,tead of the currenILl method oi h
I imp anting car IHC e 1 r1 ators in patients. ie group a so as I
F • BUILDING SERVICES AREA I discovered that this same kind of channel exists on neurons, so if  
, I I I I , further research shows these channels to be a common feature of
  ’   all excitable cells then they could have an important impact on
’ _  I    I. devising significant treatment and prevention therapies for devas-
 ° ° . .  ._ I   _ .  ... . I tating diseases of the brain such as epilepsy and Alzheimers.
I  '   Louis l·lersh’s lab group is exploring the use of gene therapy as
I a method of increasing the levels of enzymes neprilysin and
I .
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