xt7vhh6c5m0j https://nyx.uky.edu/dips/xt7vhh6c5m0j/data/mets.xml University of Kentucky University of Kentucky Chemistry Department 19770401 A brochure for the Naff Symposium, an event hosted by the University of Kentucky Chemistry Department supported by the Anna S. Naff Endowment Fund. This brochure belongs to the University of Kentucky Chemistry Department Records collection, accession number 2014ua075. archival material  English University of Kentucky Chemistry Department Contact the Special Collections Research Center for information regarding rights and use of this collection. University of Kentucky Chemistry Department Naff Symposium brochures Third Annual Symposium on Chemistry and Molecular Biology: "Studies on the Conformation of Peptides and Proteins in Solution" text Third Annual Symposium on Chemistry and Molecular Biology: "Studies on the Conformation of Peptides and Proteins in Solution" 1977 2017 true xt7vhh6c5m0j section xt7vhh6c5m0j U
C m
i; a
0:33 §. § Third Annual Symposium on
e < a
- o o
.5 2 2;
‘1’ :-
A 3 0
g g 3.
a g c H E M l s T R Y
_ a n d
5 5. § 9
5' 8 3 E
as. a a' e.
_. H H
‘g 2 2 2 4 supported by the
7< 9h 9 -l ANNA S.NAFF
g 038 g, ENDOWMENT FUND
E 3 2‘. —-
Q E 3 3
‘< ’73- g L
g~< "" I"
U)
o .
m l
Studies on the
Conformation of Peptides
and Proteins in Solution .
APRIL 1, 1977
5
«3% E
"'l — :0
E E 5 E
-| O "U 10 —{
E: E a 8 Department of Chemistry
g g D 5 g) University of Kentucky
g E m 5 Lexington, Kentucky 40506
== ‘4 e 3‘ 2 a
E > > < a
[11 E {-3 z

 Program
8:30 Coffee ~ CP room 137
Third Annual Symposium on
9:00 Welcome and IntroductIon I plan to attend the Symposium on Chemistry and
CHEMISTRY AND MOLECULAR BIOLOGY Molecular Biology.
9:15 INTRODUCTION — AMINO ACID SE-
supported by the QUENCES OF PROTEINS: THE RAW Number in Party
ANNA 5' NAFF ENDOWMENT FUND MATERIAL OF NATURAL SELECTION T—M
— Dr. C. B. Anfinsen ~
STUDIES ON THE CONFORMATION Biological function and the entire process of
0F PEPTIDES AND PROTEINS natural selection may be thought of as a series
IN SOLUTION of problems in geometry: in what ways can the
sequential order of amino acid side chains along Name M
The Department of Chemistry invites you to at- a monotonous polypeptide backbone be ar- Address
tend the third in an annual series of symposia on ranged to code, spontaneously and without m
ChemiStry and MOIeCUIar BiOlogy We aSk that YOU error) for a three.dimensiona| conformation H
tear off and return to us the attached reply form if consistent with a functionally active arrange-
you can attend. merit of atoms.
For additional information contact Dr. W. T. ————-———‘__.____
Smith, Jr. at the Chemistry Department; phone, 9230 PRINCIPLES UNDERLYING THE FOLD-
(606)'258'5178- INC AND STABILIZATION OF PROTEINS
* * * * * AND POLYPEPTIDES
— Dr. C. B. Anfinsen —
Speakers Studies on ribonuclease and other proteins have
. . . established the generality of the “thermo-
Dr. Christian B.Aannsen dynamic hypothesis”. This hypothesis states
National Institutes of Health, Chief, Laboratory of that the three-dimensional structure ofa native
Chemical Biology, NIAMDD, Nobel Laureate in protein in its normal physiological milieu is the
Chemistry in 1972. one in which the Gibbs free energy of the
whole system is lowest. Thus, the native confor-
Dr. Alan Schechter mation is determined by the totality of inter-
National Institutes of Health, Chief, Section on “9m“: interacf'ons. and he?” by the ammo
Macromolecular Biology, Laboratory of Chemical ac'd sequence, m a given enVIronment. Please detach and
Biology, NIAMDD. . . return by March 25, 1977
10:30 Discussmn and Coffee Break
* * * * *
10:45 IMMUNOCHEMICAL STUDIES OF THE
April 1,1977 CONFORMATION OF PEPTIDES AND
900 a.m.-12:00 noon PROTEINS IN SOLUTION
Room 139,Chemistry-Physics Building Dr. A‘ N' SChGChter _
Rose Street The application of immunochemical methods
University Of Kentucky to the study of the folding and conformation of
Lexington, Kentucky 40505 proteins and polypeptides provides information
about protein structure in solution which is not
Park at Commonwealth Stadium, Cooper Drive. Shuttle buses available by other Chemical and physical tech-
run to main campus. niques.
12:00 Discussion